CHANGES IN EXPRESSION LEVELS OF ERYTHROCYTE AND IMMUNE-RELATED GENES ARE ASSOCIATED WITH HIGH ALTITUDE POLYCYTHEMIA

Changes in expression levels of erythrocyte and immune-related genes are associated with high altitude polycythemia

Abstract Background As a chronic mountain sickness(CMS) with the highest incidence and the greatest harm, the pathogenesis of high altitude polycythemia (HAPC) is still not fully understood.Methods 37 HAPC patients and 42 healthy subjects were selected from plateau, and peripheral venous blood samples were collected for transcriptome sequencing on

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Restricted Concave Kite Five-Body Problem

The restricted concave kite five-body problem is a problem in which four positive masses, called the primaries, rotate in the concave kite configuration with a mass at the center of the triangle formed by three of the primaries.The fifth body has negligible mass and does not influence the motion of the four primaries.It is assumed that the fifth ma

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A Vascular-Centric Approach to Autism Spectrum Disorders

Brain development and function are highly reliant on adequate establishment and maintenance of vascular networks.Early impairments in vascular health can impact brain maturation and energy metabolism, which may lead to neurodevelopmental anomalies.Our recent work not only provides novel insights into the development of cerebrovascular networks but

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